The main thing that people misunderstanding is the actual relationship between aging and the diseases of old age – and this is largely the fault of gerontologists….people would go out and say, all the time, ‘Aging is not a disease’ – that’s not useful. Ultimately it’s very counter productive. What happened was people would think to themselves ‘well ok then, aging is this natural thing that’s never going to be amenable to medical intervention, because it’s not a disease – and also because it’s not a disease, then why should we care about it?’ – so it was absolutely the wrong thing to be saying… it’s even more the wrong thing to be saying because it’s not even true. Aubrey de Grey
Aubrey de Grey is the chief science officer of the SENS Research Foundation, which is a 501(c)(3) public charity that is transforming the way the world researches and treats age-related disease.
The research SENS funds at universities around the world and at SENS own Research Center uses regenerative medicine to repair the damage underlying the diseases of aging. The goal of SENS is to help build the industry that will cure these diseases.
Aubrey de Grey was interviewed by Adam Ford in 2012.
“When telomeres get really short that could lead to a dna damage signal and cause cells to undergo a phenomenon called ‘replicative senescence’…where cells can secrete things that are not necessarily very good for you..” Why is it that immune cells don’t work as well in older age? Listen to the interview here Jerry and…
“In short, data is not knowledge; knowledge is not comprehension; comprehension is not wisdom” The standard account of understanding has been, since Aristotle, knowledge of the causes of an event or effect. However, this account fails in cases where the subject understood is not causal. In this paper I offer an account of understanding as…
In his new book Deep Utopia, Nick Bostrom invites us to imagine a world where the big problems are solved—no hunger, no war, just a quiet hum of existential security and near infinite bliss. But then what? In a recent interview, he offers a poetic twist: “It might be completely appropriate to place more weight…
We may get a world that’s safe, rich, and unfit for humans: AI embedded in institutions could coordinate brilliantly while turning us into pampered dependents. Sandberg’s thesis: build a cyborg leviathan, but demand 2nd-order alignment – norms and institutions that keep autonomy and flourishing, not just survival. At the Future Day 2026 event, Anders Sandberg…
Bioconservatives often quote a line from Nietzsche: “That which does not crush me makes me stronger.” But alas pain often does crush people: physically, emotionally, morally. Chronic, uncontrolled pain tends to make the victim tired, depressed and weaker. True, some people are relatively resistant to physical distress. For example, high testosterone function may make someone…
Joscha Bach on GPT-3, achieving AGI, machine understanding and lots more! Discussion points: 02:40 What’s missing in AI atm? Unified coherent model of reality 04:14 AI systems like GPT-3 behave as if they understand – what’s missing? 08:35 Symbol grounding – does GPT-3 have it? 09:35 GPT-3 for music generation, GPT-3 for image generation, GPT-3…