This interview was conducted in 2012 in San Francisco. In the future may will see it is not ethically responsible to play genetic roulette and instead take the decision to have happy, healthy, pro-social offspring. 0:00 Introduction0:36 Alleviating Suffering 7:00 Justified Suffering? 13:12 Buddhism 14:42 The World Transhumanist Association 22:35 Recalibration of Society or Biology?…
The concept of digital twins combined with engineering simulation is an exciting framework for professionals working to improve medical devices in biomedicine. A digital twin acts as a virtual representation or digital replica of a physical object, system, processes which can include parts of the human body. Digital twins can be applied to medical devices…
David Pearce in interview on the The Anatomy of Happiness. While researching epilepsy, neuroscientist Itzhak Fried stumbled on a ‘mirth’ center in the brain – given this, what ought we be doing to combat extreme suffering and promote wellbeing? 0:00 Mastery of reward circuitry 0:25 Itzhak Fried’s experiments on stimulating ‘the Humor Centre’ of the…
A talk by David Pearce for the Stepping into the Future conference 2022. Synopsis: No sentient being in the evolutionary history of life has enjoyed good health as defined by the World Health Organization. The founding constitution of the World Health Organization commits the international community to a daringly ambitious conception of health: “a state…
A talk at EAGx Melbourne by David Pearce about suffering and how to get rid of it. David predicts we will abolish suffering throughout the living world. Our descendants will be animated by gradients of genetically preprogrammed well-being that are orders of magnitude richer than today’s peak experiences. David Pearce: First, I’m going to outline…
Fascinating interview with Nobel Laureate Professor Peter Doherty on the COVID-19 pandemic, the nature of COVID-19, where it came from, it’s similarities to influenza other coronaviruses (i.e. SARS, MERS), how infectivity works, what we as citizens can do to stay safe and help minimise the burden on our health systems, achieving rapid responses to pandemics,…
Congrats to Gero for the $2.2m of funding to create a drug that helps extend human life! I did two interviews with Gero in 2019 at Undoing Aging – here, with Peter Fedichev on Quantifying Aging in Large Scale Human Studies: And here with Ksenia Tsvetkova on Data Driven Longevity: Doris Yu at Tech In…
In order to achieve biomedical longevity, the problem of cross-Linking of the extracellular matrix needs to be addressed. Cells are held together by special linking proteins. When too many cross-links form between cells in a tissue, the tissue can lose its elasticity and cause problems including arteriosclerosis, presbyopia and weakened skin texture. These are chemical…
I had the absolute privilege of interviewing Judith Campisi at the Undoing Aging conference in Berlin. She was so sweet and kind – it was really a pleasure to spend time with her discussing senolytics, regenerative medicine, and the anti-aging movement. Judith Campisi was humble, open minded, and careful not to overstate…
Reason was interviewed at the Undoing Aging conference in Berlin 2019 by Adam Ford – focusing on philosophy of anti-aging, ethics, research & advocacy. Here is the audio! And the video: Topics include philosophical reasons to support anti-aging, high impact research (senolytics etc), convincing existence proofs that further research is worth doing, how AI can…
